What Are Exosomes?

Exosomes are simply put: cell signaling agents that can modulate outcomes based on the cellular needs of the environment. It can act as both a powerful anti-inflammatory or an inflammatory. Exosomes are everywhere in the body. They are nanometer-sized particles that are released from cells into extracellular fluids such as blood and interstitial fluid as well as other body fluids like saliva, urine, placenta, and breast milk. They contain a range of molecules including proteins, lipids, RNA, DNA, carbohydrates, and small metabolites which can be used to identify the cell type that released them.

1. Examining the Structure of Exosomes
2. Investigating the Consistency of Exosomes
3. Exploring the Role of Exosomes in Cellular Pathways
4. Exploring the Specific Role of Exosomes in Anti-aging Skincare
5. How are exosomes administered

The Structure of Exosomes Matters

The exact structure of exosomes is still being studied, however current research suggests that a range of lipids and proteins are found on the membrane of exosomes. These molecules appear to be involved in mediating their interaction with other cells as well as their ability to bind and transport various molecules that have interactions in cellular pathways.

Investigating the Consistency of Exosomes

Although exosomes vary in size, they have been found to be relatively consistent in terms of composition. This consistency is thought to be due to the cellular pathways they travel through which enables them to maintain their structure and integrity. As such, this makes them an ideal way to transport molecules both intra- and inter-cellularly.

Exploring the Role of Exosomes in Cellular Pathways

Exosomes play an important role in cellular pathways, as they are responsible for transporting molecules such as proteins and nucleic acids between cells. This enables cells to communicate with each other, facilitating various processes including differentiation, proliferation, and metabolism.
Also, exosomes have been found to be involved in mediating immune responses by carrying immunomodulatory molecules which can influence inflammation and even cancer progression. Overseas in Europe, it has also been studied in orthopedic cases to alleviate joint pain and degeneration and brain issues such as Alzheimer’s disease and dementia.
In aesthetic medicine, exosomes have been used to improve the skin cell pathways of collagen production, and to improve the anti-wrinkle defense.

Exploring the Specific Role of Exosomes in Anti-Aging Skincare

Exosomes are becoming increasingly popular as an ingredient in cosmetic skincare products due to their ability to improve cellular pathways that can reduce signs of aging. In particular, exosomes have been used to modulate collagen production which can help improve skin texture, reduce wrinkles, and even out skin tone. Also, they can also increase epidermal growth factor receptor activity which helps cell regeneration and repair processes in the face.

How Are Exosomes Administered?

Exosomes can be administered topically, intravenously, or injected (subcutaneously or intramuscularly) locally depending on their intended use. Topical administration is typically done with creams or serums that contain exosome proteins and lipids which help to target specific areas of the body. Intravenous administration is typically done with a suspension that contains exosomes and is thought to provide systemic benefits such as increased immune function.
On the face, it is administered through a specific protocol developed by Redox Medical Group. It starts with a specific exfoliation that provides the freshest facial surface, followed by depth-targeted microneedling with topical exosome application. The aftercare is just as important as the procedure itself. Hydrating the body with plenty of mineral water, liberal application of specific post-care topical skincare products, and follow up visits will ensure the cellular activity of the exosomes.

Not All Exosomes are Created Equal

Exosomes are meticulously derived biological products that must go through a rigorous testing and filtration process that rids the exosomes of toxins, pathogens, diseases, particulate matter, and maintains sterility throughout the entire process.

1. It doesn’t require a special -80 degree freezer. If your exosomes come freeze dried, it is NOT an exosome. It is as simple as that.
2. Some fake products boast that they have more exosome particles than their competitors. This doesn’t mean anything if their product is freeze dried. Also it’s not about the quantity of the exosomes, it’s about the quality.
3. The price. Remember, the exosomes must go through rigorous testing, the specific filtration, and the lab sterility practices make this an expensive product. If you’re being sold an exosome at a cheap price, you’re definitely not buying exosomes.
4. They’re not derived from stem cells. Remember, exosomes exist in all cellular fluids. if it’s not from a stem cell it won’t have the regenerative qualities we are looking for in anti-aging. Ethically, this is derived from a specific cell bank that houses demographically ideal placentas.

There is only one company in the USA and Europe that meets such quality standards – Kimera Labs. They do 3rd party lab testing, follow strict lab sterility practices, have a proven record of cell bank derivatives, and continuously provide exosomes for medical research around the world for several clinical trials from Alzheimer’s, Lung cancer, Wound healing, and more. If you’re using exosomes from another brand – you are not getting exosomes. It’s just that simple.

Conclusion

Exosomes are small but powerful particles that are involved in a variety of cellular pathways, including anti-aging skincare. Their consistent structure and composition make them ideal for transporting molecules between cells, while their immunomodulatory properties can help to reduce inflammation and increase collagen production. These characteristics make exosomes an attractive option for those looking to maintain healthy youthful skin. But, it is an expensive treatment because the product goes through such a rigorous process before becoming approved for patient use. Make sure to ask if it’s a Kimera Lab exosome, otherwise, we simply cannot recommend its use.
It’s the only exosome brand we at Redox Medical Group use because of those characteristics.

Call us for more information (310) 421-2707.