What is Redox?

Overview

In the first episode of the Redox Revolution podcast, host Dr. William Seeds introduces the concept of Redox, highlighting its vital role in healthcare and the importance of consulting healthcare providers before making health-related changes. He defines Redox as the balance of cellular processes fundamental to health, emphasizing the role of antioxidants in managing cellular stress.

The conversation shifts to the significance of peptides, including insulin, in cellular medicine and their growing industry relevance. Dr. Seeds stresses the necessity of individualizedpatient care over rigid protocols, advocating for stronger communication between healthcare providers and patients. He explores how peptides function as signaling agents, optimizing cellular function, and shares practical health strategies—such as walking after meals to improve insulin sensitivity.

The episode wraps up with a teaser for the next discussion on GLP1s, featuring guest Jock Putney. Dr. Seeds invites listeners to engage, ask questions, and join the Redox Revolution in redefining modern medicine.

Notes

Introduction to Redox (00:00 - 01:10)

• Redox Revolution is introduced as a new podcast series.
• Emphasis on the importance of understanding Redox in healthcare and healthspan.
• Listeners are advised to consult healthcare providers before making health changes.

Understanding Redox (01:10 - 04:00)

• Redox is defined as a balance of cellular processes, crucial for health and disease.
• The importance of antioxidants in managing cellular stress is highlighted.
• Dysfunction in Redox can lead to various health issues including metabolic and immune problems.

Importance of Peptides (04:00 - 07:30)

• Peptides are discussed as significant players in cellular medicine.
• Insulin is identified as a peptide that changed the medical landscape.
• The growth of the peptide industry is noted, with projections for future growth.

Protocols vs. Individualized Care (07:30 - 12:00)

• The discussion emphasizes the need for individualized care over strict protocols.
• Healthcare providers should focus on understanding patient needs rather than following set protocols.
• The importance of patient-provider communication is stressed.

Peptide Mechanisms (12:00 - 18:00)

• Peptides are explained as signaling agents that help cells adapt to stress.
• The role of peptides in enhancing cellular function is discussed.
• The conversation highlights the need for healthcare providers to educate themselves on peptides.

Postprandial Health (36:30 - 44:34)

• Walking after meals is recommended to manage postprandial hyperglycemia.
• The discussion highlights how walking can reduce stress on beta cells and improve insulin sensitivity.
• The importance of lifestyle changes in managing health is emphasized.

Future Discussions (54:00 - 54:47)

• The next episode will focus on GLP1s and their implications in healthcare.
• A special guest, Jock Putney, will join the discussion.
• Listeners are encouraged to engage and ask questions.

00:47
Dr. William Seeds
Hello everyone. I am excited to be here today to introduce you to the Redox Revolution. This is our first podcast and I cannot tell you how excited I am to start this new revolution of understanding what we do here at Redox and how we're going to change the world. 

01:09
Matthew Seeds
Why are we here? What is Redox? What's the Redox Revolution? Why are peptides important? Why is this such an important topic to actually start to get a grasp on? 

01:21
Dr. William Seeds
Redox is going to be something that I am going to ingrain into the world today for everyone to understand that this is where, this is the beginning of understanding everything in healthcare, everything in health span, not longevity, healthspan and how we work on understanding pretty much, I think, everything that has to do with medicine and everything that has to do with life, everything that has to do with the. The meaning of what we do as a medical group in enhancing cell function, in making people healthier. So let's define Redox. Redox is basically a word that is. It's about homeostasis. It's about keeping the yin and yang of a cell intact, right? It's, it basically it's. The cell has to deal with so much stress in a day and then how does it handle that stress? It makes antioxidants. 

02:41
Dr. William Seeds
So the antioxidants have to take care of the stress and they all have. We have to live together and be happy. So it's a modulation, it's a, it's a place of where. And this is talking in general terms again just to understand. It's a way of understanding that life and disease really are all about balance. That's it. It comes down to balance of energy. And that's where everything starts. When things go bad, redox gets dysfunctional. There may be too much antioxidant, there may be too much oxidative stress, there's an imbalance and then shit goes bad. And that's it, that's the beginning of understanding how we look at the normal aspects of how a cell works, and then how does that lead into metabolic problems? How does that lead into immune problems? How does that lead to disease? How does that lead to cancer? 

04:02
Dr. William Seeds
How does it improve performance? 

04:05
Matthew Seeds
So with the table set there, then what makes peptides so important? Because the big player right now is all the GLP1s. Everybody knows what those are, right? It's actually kind of bringing peptides into the public conscience and making it a little bit of a, you know, forefront of mind topic. Everybody knows what it is now. You've been talking about these things for over a decade now. It's actually here. So with redox in mind, why. Why do people know. Why do people need to know how to use peptides appropriately? 

04:36
Dr. William Seeds
So peptides, historically, peptides. When I started introducing peptides to the world and teaching peptides to the physicians, it was actually a way for me to introduce cellular medicine. It was a way for me to start talking about redox. 

04:57
Madison Lepore
I think it's really important for you to mention what the first peptide actually is or was because I think that'll shock a lot of people. 

05:08
Dr. William Seeds
So. 

05:08
Matthew Seeds
Certified hall of Fame peptide. 

05:10
Dr. William Seeds
Certified hall of Fame peptide. So you're, man, you're just pulling out the, like, I read your book. You're the intellectual genius that you have. So what Mattie's saying is when we're talking about peptides, I mean, we're going to jump into a lot of things. But what people don't realize, when I started my lectures on trying to introduce cellular medicine, molecular pathways, redox, and some aspects of quantum physics and cell function, at the very beginning when I would start, I'd ask all my physicians out there, who uses peptides? Because nobody really knew what they were and nobody raised their hands. And I would say, well, who uses insulin? And everybody be like, I said, insulin's a peptide, guys. Insulin's a peptide. 

06:04
Dr. William Seeds
And so that was a great way to start capturing my peer group and to get them started to understand that, hey, peptides are, in this instance of comparing it to insulin, were. And by the way, you know, insulin changed the world. It was incredible when it became a synthetically made. I mean, I could get into all those issues, but it was a great way to capture my peer group in starting to want to understand more about redox and the molecular mechanisms that create health and disease. And so that was, that was a long time ago and it's morphed into this area now of where we see this word peptide. 

07:11
Matthew Seeds
It's a whole industry. 

07:12
Dr. William Seeds
It's I mean, it's insane. It's like, what the heck? When we started this, it was. Nobody knew what a peptide was. Nobody. It was not even mentioned. And in fact, when we first started, we could barely get people to come and listen to what I was saying. 

07:29
Matthew Seeds
Well, now you can't keep the money out of it. Like as recently as 20, 23, it's like a $45 billion industry, and it has a bellwether. GLP1s make up like 37 of that 45 billion. But I mean, you'd. You look at any projection down by the 2000 and 30s, it's supposed to be somewhere between a 400 and $500 billion industry. And I think that goes back to your original point of why it's so important to realize what's true, what's not, who's pushing the right messaging. Because when an industry blows up like this, you have a lot of players who are trying to get into it for the wrong reasons. So that's why all this stuff you're talking about is important. 

08:10
Dr. William Seeds
Well, and that's why I have you here, Matt, because you're in touch with that aspect of what's happening in the world. My, my job is just to know the science. My job is to introduce the science, teach the science. But let me take this one second and just say, look, I, I get really upset out there when I see people talking and promoting themselves as experts and reading a piece of paper because they read an article and they're, and then they're selling something behind it or they're trying to build a following because they want to show that they've got some knowledge. I want everybody to know that I've got a knowledge base that's like, not very big right now and it needs to expand. I look at myself as an educator, not an expert, because there's so much we don't know. 

09:17
Dr. William Seeds
But what I can say is that I'm a practicing physician that has actually been doing this and working with these mechanisms and working with understanding how to make signaling agents like peptides or repurposed drugs or small molecules or supplements work to figure out problems. And, and that's what, that's where. When, when this all started, I wanted to teach healthcare providers how to think. Not that they weren't, but it's. The medical agenda in medical school is to shove this bullshit down your throat that is kind of pushed by big pharma to some degree in understanding what they want. And this is a protocol. This is a protocol. This is a protocol. What do we always hear from all of our new people? Joining is like, just give me the protocol so I can do this. Well, that's not. That's not what we're about. 

10:24
Dr. William Seeds
We're about thinking. We're about. We're about thinking through the process, looking back, because if you have the knowledge of how a cell functions in a normal way and how it reacts to exercise or sleep or a good diet, if you know these molecular pathways, you've got the keys to the kingdom. You. You can start thinking about, okay, what's gone wrong, and then work with your patient. Tailor in these aspects of peptides, which, again, were a way to start in talking about molecular pathways and redox and help us to improve a metabolic process or an immune process or. Or whatever in where it's always different with individuals. So protocols never really work. It's like, you gotta think about this. So. 

11:28
Matthew Seeds
And that's the key part. You bringing up the individual, you bringing up the patient. And that's why it's been so different with the community you've built. You're on the front lines, you're seeing hundreds of patients a month. You're seeing thousands of patients a year. I mean, Madison, what's the differences you've seen just between reading a white paper and actually applying it in a clinical setting? 

11:49
Madison Lepore
There's absolutely no. You can't just have the white paper and then follow it, because that patient's gonna fail. Because every patient is different. And we may start off with, this is usually what we do. This is usually the dosing regimen that we follow, but I would say probably 80% of the time, at least, we have to make alterations to make it fit that patient, and we make it work for them. 

12:14
Matthew Seeds
So you're saying, basically what the two of you are saying is you need to take the term protocol and reframe it. Not as a set of permanents. This is what you're always going to do. But a protocol should just be kind of the starting rubric that you're going to need to mold for each individual person, continue to work with them, continue to see essentially how the pathways in their body are taking it. Because even though everyone's is supposed to work the same, they don't. 

12:38
Dr. William Seeds
We've seen that's not the case, and that's brilliant. 

12:41
Madison Lepore
But I do think you should say, like, what is a peptide? Like, you're talking all about the peptides, but when I was in my job interview for this job, I Didn't know what a peptide was. 

12:51
Matthew Seeds
And, you know, as the ssrp, when we have tried to exhibit at events in the past, we'll have people coming up to us because one of our core competencies is peptide therapy certification. That's like the core training that people want when they come to the institute. And a big question we get is people coming up to the booth saying, well, what are peptides? And recently, at least at those events, I mean, you can almost always in the ceiling, find the giant Novo Nordisk display just hanging from the rafters, and you're like, those are peptides. Yeah. 

13:23
Madison Lepore
So, but, like, what is a peptide? 

13:27
Dr. William Seeds
Red flag when somebody's out there promoting, hey, we're going to teach and give you protocols to make you this better doctor or this better health care provider. Or you should run like the. It's like, come on. This is all about we. This is why certification. This is why our certification. We spend so much time on making it. Making an environment where you gotta think. You've got to work with an individual and think through a problem. Medicine is all about listening to the patient. You know, this is bringing back medicine to the patient. Right? This is bringing back empowerment to the patient. This is like letting the patient know we're listening. Again, we. I mean, how does it work, Maddie? I mean, when we work with our patients, we listen because that's how we make adjustments. 

14:30
Dr. William Seeds
That's how we work with them in understanding how well are we working with these pathways. Now, I'm not going to discredit biomarkers and lab tests and things that we use to help us, help guide us, but that relationship with the patient, that's the holy grail. That's it. That's where we make a difference, and that's what we try to convey in our certification. And everything we're doing with SSRP is, let's go back to owning this. Let's think through the problems. Let's make a plan based on the patient. Let's not shove a goddamn protocol in your face and say, here we go, and then they come back and go, I'm no better. 

15:17
Matthew Seeds
It didn't work. 

15:18
Dr. William Seeds
Didn't work. 

15:20
Matthew Seeds
I want to. I want to pull something out that you just mentioned, something that you two both have to deal with a lot, because especially when you get referrals, right? Or a patient coming to you for the first time who maybe did one of these celebrity panels. Biomarkers are important, but what has been the biggest gap in terms of information and actual application when it comes to people taking these Tests and being like, Here are my 1000 indications and results and biomarkers. That's a lot of these things right now is. It's. It's almost like it's the blood version of this full body mri, right? People are taking all these different measurements and how many of them are actually useful. It's like, there's so much information out there. How do you dwindle it down and how do you actually pick out what can be. 

16:09
Dr. William Seeds
That's an interesting conversation in itself because sometimes the patients feel they're here for one reason. And then once you start the questioning and you get them involved in the dialogue, which they typically. We find so many times that hasn't been the case. It's been. It's been. They fill out a. A form and they only get to talk for so long and they only get in the office for so long. And then the doctor or the healthcare provider is like, okay, here's what we're going to do based on. Because they've done studies ahead and they've said, well, this is wrong. We're concentrate on this because this is what your lab values say, or this is what this new MRI shows that, oh, my gosh, you've got a cyst here and you've got something here and we need to do more testing. 

16:59
Dr. William Seeds
The patient's just like, is this why I showed up here? And, oh, you're going to take me down that pathway where I got to pay for more testing and more testing. That's what we hear. And it's amazing the stuff people come in with, stacks of information. And I always look at it and go, what are people doing with all this information? You know what? Because it's a matter of what's. Oh, gosh, we could get into so many things about these tests. 

17:34
Matthew Seeds
No, and I kind of want you to. That's kind of the reason why I wanted to pull that part out, because I just feel like that's one of the biggest gaps and healthcare understanding right now. You have all of these celebrity providers or corporate entities who are pushing these panels that include more markers and more biomarkers and more testing and how much of it is actually useful. 

17:59
Madison Lepore
It's important to note too, on that you have them pushing more testing. With this test, this is a supplement you take. With this test, this is a supplement you take. So it's the testing, but also pushing their products at the same time as the testing. 

18:15
Matthew Seeds
I understand it's important to kind of keep a gauge on what's going on in your body. But it just feels like people are getting pushed down a never ending road of tests instead of trying to actually work towards the solutions. 

18:30
Dr. William Seeds
Well, number one, people, I think people have been misled that feel that markers are the way to follow things and that this is a judge of how you are getting better when. 

18:42
Madison Lepore
When they even say I feel better. But this test showed that my age had decreased or like my methylation had decreased. And it's like, let's go on how you're feeling. 

18:55
Matthew Seeds
That's so important because I mean, you're both still wearing these whoops. We all got right. I'm, I've taken mine off at this point because there'd be some mornings where I wake up, I feel great and then I look at my score and it's like, oh, you slept like crap, you're a 51%. And then all of a sudden it's almost like a. 

19:16
Madison Lepore
It's in your head. 

19:17
Matthew Seeds
It's in my head. I'm like, but I thought I felt good. And then the rest of the day I'm like questioning like, do I really feel good? And so then I just got in the habit of only checking it like once a week. And now I've just taken it off. 

19:28
Dr. William Seeds
Entirely because I, I know I slept. 

19:33
Madison Lepore
Great and I'm like, I didn't sleep at all. And so I've really, I haven't much. 

19:38
Matthew Seeds
So at the end of the day, what matters to you? What it says or how you feel? 

19:41
Dr. William Seeds
How you feel, how you feel. So, so this is another. I'm getting so jazzed over all this stuff. Information is what you want to make out of it. You know, getting some data on sleep, getting some information. It can be helpful. But yeah, it can be overdone. Right? Because we'll get into all these things with redox here about why things don't match up. But they're just numbers. They're just numbers and it's just a place to start. But let me say one thing. This whoop when you go like this at night, you can find the toilet and go to the bathroom. It's pretty cool. 

20:19
Matthew Seeds
Yeah, I mean, everybody has. 

20:20
Dr. William Seeds
Because it has this little light underneath and you're just like, that's why I don't take it off anymore. Because I'm like, damn, I can navigate through like the hotel or, you know, wherever I am, I can see that toilet. 

20:33
Matthew Seeds
And I'm like, yeah, everybody finds the aspects they like. I liked how after six months of wearing it basically said you need nine hours and 11 minutes of sleep on average. I learned what my body needs to sleep and I need that much sleep because I'm so much bigger than you. 

20:49
Dr. William Seeds
Oh. 

20:50
Matthew Seeds
And I, I need that sleep because. 

20:53
Madison Lepore
Can you hear? He skis faster than you too. 

20:55
Dr. William Seeds
Ooh, let's not even get into skiing right now. No. 

20:58
Matthew Seeds
And the other part I liked was the hepatic alarm. I liked little vibrate. That was nice. If anybody knows a non whoop hepatic alarm that you can wear, please put it in the comments because I would love to find one. 

21:12
Madison Lepore
I think we have those where the bed, like you can put it in your bed and wait. 

21:15
Dr. William Seeds
I actually like, I love this as an alarm. No, that's what I'm saying. 

21:19
Matthew Seeds
I'm saying I love that part. 

21:20
Dr. William Seeds
Well, I like this. So I like the information as data in. 

21:24
Matthew Seeds
It's like a panel. He's taking out the parts he likes. 

21:26
Dr. William Seeds
Listen, listen, listen. Stop, stop. I like, I like having the information, you know, the heart rate variability, the oxygenation, the thought. 

21:37
Madison Lepore
You don't like heart rate variability. 

21:38
Dr. William Seeds
Well, you need a lot of data, right? And it, and it's depends on what you're doing to change that. Otherwise high heart rate variability can drive you crazy in looking at these numbers. 

21:49
Matthew Seeds
Well, you've got a bit in terms similar to a protocol, right, where everybody's heart rate variability is different. The same. 

21:56
Dr. William Seeds
Yeah, everybody's different. And that gets back to this aspect of taking care of patients. All right, that is the, that's the gold here. And that's where, that's why when somebody sits here and reads you a paper, especially if they're holding it in front of themselves and kind of referring to it and reading to you. Well, that's okay. He's, he's got to do his questions. I'm just saying if you're promoting yourself to be a, an expert on, in social world social media and stuff, it's like, come on guys, look at all the red flags here. It's like you can't just because you read a paper and this is what it says, doesn't necessarily, it doesn't mean that's what's going to happen. It doesn't mean it's like this word longevity, right? Because you increase a telomere and you're going to live longer. Does that mean great? 

22:51
Dr. William Seeds
Hell no, it doesn't. Because people still have disease, people still have problems and their health sucks and their life sucks, but they're living longer. What the fuck is that? 

23:02
Madison Lepore
Come on and aren't they living longer? Cuz their cells have just downregulated. 

23:09
Dr. William Seeds
Damn, she's brilliant. So she's living in the world of how we take care of patients. So perfect example. Great thing to bring up, Maddie. 

23:18
Madison Lepore
Thank you. 

23:19
Dr. William Seeds
Great example. Here's something to think about. And this is where we're going to go with this show. This is why this is so exciting to get into the aspects of real life. Post Covid, people with post Covid fatigue, people with problems of where all of a sudden their life has changed. They got through a disease, but they feel like shit, they have no energy, everything's changed. Well, okay, the cell has. Look at it from the cell function. And this is a generalized description. The cell has said, hey, I've been hit with this. I've got so much going on. I'm trying to deal with this crazy virus and what it's done to my metabolism and what it's done to my. The way I'm supposed to handle life. And the cell goes, screw everybody else. I'm going to downregulate myself just so we can survive. 

24:19
Dr. William Seeds
And when it does that, you pay the price, right? You can't adapt, you can't. Life isn't great because that cell has found a way to survive. Cell's just brilliant. Cell is brilliant. And that's what we're going to learn here in Redox. How brilliant the cell is and why peptides, which are just signaling agents, and why understanding what we do is about bringing the brilliance back in the cell, not manipulating it with molecules and drugs and doing things to tell the cell what to do. The cell is brilliant. 

24:54
Matthew Seeds
You're saying it's. Redox needs a. Oh my. 

24:59
Dr. William Seeds
Redox needs a revolution. Thank you. 

25:02
Madison Lepore
Imagine after all those rabbit holes, we kind of briefly touched on what the. 

25:06
Dr. William Seeds
Original question was, what a peptide is. Okay, so a peptide. So what is a peptide? A peptide is basically an amino acid that is bonded to another amino acid by a what? 

25:24
Madison Lepore
Peptide bond. 

25:25
Dr. William Seeds
Peptide bond. That can be a chain of amino acids of 22, 3, 40, 50. And then it gets into being a polypeptide when it's, you know, above 50 maybe. And then when it gets even bigger, it becomes a protein. So protein, polypeptide, peptide. Because when we take proteins in from our food, like say you eat a steak or you eat some fish, or you eat something that's got protein that's broken down, you know, once you eat it's broken down into protein. Well, that protein is broken down into a polypeptide and then a polypeptide is broken down into a peptide. So it's kind of cool that these are signaling agents that are absorbed in the body that start doing some amazing things. 

26:23
Dr. William Seeds
And so there are these amino acids that have specific jobs in roles in working in a cell, in helping with adapting to everyday life. And that means telling the nucleus to do things, telling the mitochondria to do things, telling the peroxisome to do things, telling the ribosomes to do things. These are things in the cell, by the way, that mean something to me, that get me excited. And. And my job is to work with understanding how all of that works, which we have so much science and so much. You know, you. You grew up watching your dad just have a problem with reading, right? That's what I was reading when you were this guy who said, hey, dad, you want to play Xbox right now? I say, nah, I'll get to you in a little bit. 

27:28
Matthew Seeds
I didn't want to play Xbox with you. I wanted to play Xbox with myself. You were terrible at those games. 

27:33
Dr. William Seeds
You kidding me? Brutality. Anyways, okay, so the peptide. 

27:40
Matthew Seeds
Go ahead. 

27:41
Dr. William Seeds
Peptides. 

27:42
Madison Lepore
What's really important for people to know about peptides, they're not blank to your body because your body. 

27:48
Dr. William Seeds
Oh, great. Gosh, this is cool. Yeah. So peptides. I know where you're getting. So peptides, normally, so we're talking about food, but the body makes peptides for different reasons for signaling, to talk. It's how the body talks. Let's just use peptides as an example. Peptides can be enzymes, they can be transcription factors, they can be hormones, they can be signaling agents. So what you're saying is when a cell, let's say, has to. You wake up, and you have to start adapting to the day. And the cell says, okay, let's wake up, and we need to do this. So it starts sending signals. Right? And those are signals that the cell is familiar with. Right. The. And other cells are familiar with, and organs are familiar with those. Sig. What happens with those signals? It's how everything communicates. 

28:51
Dr. William Seeds
So when we talk about peptides that we're utilizing, we're using peptides, or synthesizing peptides that represent something that's made in the body. So the cells are already familiar with the messaging. They're like, oh, this is. We're. We're okay with this. We're not. 

29:14
Matthew Seeds
And leveraging an existing blueprint. 

29:17
Dr. William Seeds
Yeah. Oh, whoa. Big word, multiple syllables. 

29:22
Madison Lepore
Yeah. 

29:23
Dr. William Seeds
Whoa. 

29:24
Madison Lepore
Have to definitely count the chin drops on that one. 

29:26
Matthew Seeds
So if you were going to bring those strategies into a practical approach. Right. Because I'm sure in later episodes we will get into how appropriate it is. 

29:36
Dr. William Seeds
We better get into this stuff. 

29:38
Matthew Seeds
We'll get into, you know, appropriate sourcing and what compounding is. But just when people are walking around grocery store cvs, they see peptide everywhere. Now in the cosmetics, isn't it dietary. 

29:51
Dr. William Seeds
Supplements, isn't that just, it's mind boggling where there is no peptide in the world. I mean there was no discussion of anything and now look at it. It's just I, I never imagined this would happen. 

30:06
Matthew Seeds
Well, and that's kind of the point I want to get to with it just being slapped onto every label. Now what's important for the everyday consumer to understand about, okay, it says peptide, but is that actually something that's going to be able to do the role that it's advertised to do? 

30:23
Dr. William Seeds
Boy, that's a great question. And that's so that's where so much misleading information is out there. 

30:30
Matthew Seeds
What's a clinically viable dose? Is it even in a way that, you know, is the stomach acid going to destroy it? Is it going to be able to be absorbed into the skin? I mean, there are so many factors at play. So what should people be looking out for when they are, you know, walking down the aisle? If something says peptide, are there a few, couple shortcuts or checklists that they should be going through to see if that's something that's actually going to be useful for their day to day routine? 

30:57
Dr. William Seeds
Yeah. Wow. That's why they got to keep listening to the show because we're going to get into this so deep. It's, it's the wild west out there and there's so much behind this word peptide and people believe that because of peptides in it that it's a functional peptide, it's a biological peptide and actually a lot of times that's just not the case. It's, it's, yeah, it's a peptide and yeah, it may be used on your skin or it may be something that it's added into a supplement or a food group, but most of the time it's useless. 

31:42
Matthew Seeds
Proprietary formula. 

31:43
Dr. William Seeds
It's a no idea how much is in there. A proprietary formula that really bothers me when I see that. But that's where we're going with this show. I mean this is what's so exciting. I'm not saying exposure. I just want to make people smarter and I want people to just Feel empowered that when they see something or they understand that they're not, they're being manipulated by marketing in this word peptide right now. 

32:09
Matthew Seeds
Well, being manipulated by marketing, you could take it back to the patient care approach of a protocol. They're trying to give you a protocol of. This is how you need to understand things. And basically the message that you are pushing is, listen, you need to understand that none of us will ever understand all of this fully, but you need to have the right mindset, the right approach, so that you can continue to learn and continue to make the most informed decisions. 

32:32
Dr. William Seeds
Well, absolutely. So in respect of what? You know, looking at these consumer goods that are out there with pretty much everything now has a peptide in it. It's a marketing tool. You know, and this is real science where you have to understand that a peptide is a functional, it's a functional biological agent that has a purpose. 

33:00
Matthew Seeds
No, and this is a key point that you've made over time. It's a functional peptide for multiple reasons because peptides are there to help optimize you, not cure you. And that's a point that you've made a lot. They're there to optimize you because you gotta make sure that yourself are functional. I mean, in your book the Redox Promise, you really touch on the three pillars of just sleep, diet and exercise. And everybody knows what those are, but what are some just practical takeaways that are so important to keep those things in line so that if somebody wants to use peptides, they can actually be helpful. Because if you're, you've said it before, if you're just putting peptides in, but you don't have everything else in order, they're not really going to do a whole lot. 

33:45
Matthew Seeds
They might take you from 30 to 40%, but what is that? That's still a failing grade. 

33:50
Dr. William Seeds
Well, that's a great, that's a great lead into actually what we do. So you've touched on sleep, exercise, diet. Right? Okay. Those are the pillars of life. I mean, those are what control and manage Redox or work with Redox. They're, they're what, they're the ultimate in improving health span. Right. And we have all of this literature and science on exercise, diet, sleep. We, we got a tremendous amount of information on how that leads to optimization of our lives. Right. And how it mitigates disease, how it stops the process of disease and other things. And if we understand that, how that works, and we understand, then we look at the molecular mechanisms and these cellular pathways that let the cells communicate and do their job to maintain those states. Well, then we've got. We've got a little bit of information that can be very useful. 

35:17
Dr. William Seeds
And peptides are a way to bring back that cell's ability to take advantage of sleep, take advantage of exercise, take advantage of nutrition, or work with it to optimize the cell. 

35:35
Matthew Seeds
So would it be appropriate to say that if you have your sleep, diet, and exercise in order, peptides can help you get from that, say, arbitrary 90% back to a hundred percent? But peptides aren't gonna help you at all if you don't have those basic fundamentals. 

35:54
Madison Lepore
Peptides aren't gonna do it for you. You have to also do them work. 

35:58
Dr. William Seeds
Well, what's. So this is a great dialogue because the answer is actually both. It's two pronged. It's yes, it can do what you're saying, but also it's a tool as a clinician, and I'm working with someone who doesn't give a shit about sleep, exercise, or diet, who just comes to you and they're in a bad place. These peptides are an amazing tool to get the patient on your side, to get the patient dialogue started of where I can make inroads. I'm not going to cure them. I'm not going to make things like I could if they did all those things right, but I'm going to get somewhere where I can turn the cell on. And the cell says, oh, my gosh, I've got some signaling and I can start doing some good things. And then. Let me, let me finish. Yeah, go. 

36:52
Dr. William Seeds
And, and this is so cool. This is so cool. I get to talk about this stuff. And the cell then says, hey, let's do this. And then you're talking to your patient and, you know, it's. They're like, yeah, maybe something's happening. Yeah, I feel a little bit better. And then they're like, doctor sees, is there more I could do here? Is there more? And you're just like, yes, patients starting to ask me questions. Patients like, I'm getting into this dialogue where, here we go. 

37:27
Madison Lepore
They become their own zealots. 

37:28
Dr. William Seeds
They become their own advocate. They become their expert in wanting to know more about themselves. But they're. They're exploring how they can improve their lives. They're not depending on me anymore to be like this miracle worker or whatever they think I am, which I'm not. They're bringing back this dialogue relationship. And hey, Doc, empower me. And let's keep going. So it's a great tool to get the process started. And then you introduce diet, you introduce exercise, you introduce sleep, or talking about these things. And it's always different with everybody. It may be diet here, maybe exercise here. And then once exercise starts, they say, hey, can I eat better? Can I do something better to improve muscle protein synthesis? And you're like, what did you just say? 

38:24
Matthew Seeds
And this is. Wait to bring it. 

38:26
Dr. William Seeds
I go, what did you just say? And they say, muscle protein synthesis. And I'm like, I'm getting excited. This is their talk in my language. 

38:35
Matthew Seeds
So bringing this conversation all the way back around then. So what you're saying is jumping from that 30 to 40% actually is insightful and it is helpful. And maybe we shouldn't be focusing on the grade, but focusing on the upward trajectory and momentum. 

38:49
Dr. William Seeds
Absolutely. That's very good. That's awesome. Yeah, because that's exactly right. It's. It's momentum. That's what we always talk about. 

38:58
Madison Lepore
They need to feel it, because if they're not feeling the changes, then you're not going to get anywhere. They need to feel it because we need our brain to also buy in. But I don't like saying buy in because it's sounds like what. 

39:10
Dr. William Seeds
But you're right, because the brain. What people don't realize is there's a lot of noise out there. And the. Your brain is brilliant, too. Your brain is like always on and trying to figure out where to go. 

39:25
Madison Lepore
And, and it's powerful. 

39:27
Dr. William Seeds
It's so powerful. There's so much we don't know. 

39:30
Matthew Seeds
So how do you drown out the noise? What are some early signs of cellular dysfunction that you can start to pick up on, to start to go, huh, Maybe I need to look into this more. Maybe I need to start asking my. 

39:40
Madison Lepore
Doctor the right questions, how they're feeling, like, oh, I'm holding on weight that I used to not hold on to, or I'm more fatigued than I used to be. I get sick more often than I used to. But then once they're patients and we start them, we just, we let them feel the difference. 

40:02
Dr. William Seeds
A lot of times it's. And yeah, it's different with everybody. It's, it's. Look, my skills as a physician only get better if I get better at asking questions. And I learned from my patients how to ask questions a lot. From our patients. We learned so much because everybody's different and everybody brings things out a little differently. And you've gotta be. You've gotta develop those skills. And what. I've been doing this for over 30 years, and I'm still just learning, you know, I'm. I'm still learning how to ask questions. And. And it's amazing when, like, so you can ask. You can take a patient and say, you know what? Let's stop here. Let's look back at your last week. How did you handle this last week? What. What were things that were more difficult than maybe 10 years ago or five days ago? Or you. 

40:58
Dr. William Seeds
You. You find ways to get them to look at things and go, yeah, I'm actually. I'm having a harder time dealing with, you know, I take the kids to their soccer games, to this, to that, and, oh, yeah, by the way, I'm really. I think I'm worn out because I'm all over the place. You just get. It's amazing what comes out, and it's important. 

41:20
Madison Lepore
And I feel like that's part of really what patients love about Redox is we never discredit anything they're saying, because anything is possible. 

41:28
Dr. William Seeds
Oh, you can't. That's. That's exactly right. 

41:30
Madison Lepore
And that's how we learn a lot. Like, it might not be a side effect that is typical or that we've seen, but we don't discredit it. And then months down the line, another patient might say the same thing. We're like, oh, like full circle. It has happened before. 

41:46
Matthew Seeds
So you guys talk a lot about working with patients on an individual level, but what is a universal truth? What is this episode's performance protocol that anybody can start to apply today? 

41:59
Madison Lepore
Go for a walk after you eat. 

42:01
Dr. William Seeds
Oh, my gosh. That's just so that she just hit. 

42:06
Matthew Seeds
Yeah, go into that a little more. What do you mean? 

42:08
Dr. William Seeds
What Maddie is referring to here is the most dangerous time in your life is eating. People don't know this. This is what's so cool. This is so cool because when you eat and you take food in your cell, your. Your body has to all of a sudden turn on and do something with that food, right? So it's. And it. It all comes down to this process of where this beta cell in the pancreas is like this sensor for glucose, and it says, game on glucose in what are we going to do? So what she said walking. Why do we walk after we eat? Why have we pushed that message? I don't know how long ago. And now you hear everybody talking about it, and actually we get some good. Our mind pump boys are really cool because they bring it back. Hey, Doc. 

43:13
Dr. William Seeds
Talked about this. And I'm like, oh, my God. Somebody who actually gives us credit for doing something right. Gotta love it. Gotta love those mind pump boys. So what does walking do? So let's say we eat. Okay? We eat food. Isn't this cool? We eat food. We just think of it as food, as building up glucose in the body, right? That beta cell in the pancreas is gonna pull glucose into muscle. It's gonna pull glucose into everywhere it needs to by making insulin, right? Insulin is the key to life. It's gonna burn, bring glucose into the cell, because it's. It has those mechanisms to do it. So it's going to lower glucose, right? It's supposed to after you eat. Well, you eat. There's so much glucose that comes in right after you eat that there's this spike of glucose. It's a spike. 

44:04
Dr. William Seeds
And insulin has to spike up to meet that too. Well, guess what? Walking, Walking after you eat does what prevents that spike? It prevents that spike of glucose, which can be so dangerous because that glucose has to be utilized. Well, when you're walking muscle, all of a sudden, exercise, this is the beauty of exercise. It doesn't need all of these signaling things to happen. It just says right away, I want glucose. So all of a sudden you can take care of that, what we call postprandial hyperglycemia. You can reduce that glucose right away. Well, what are you doing when you do that? You know the answer. You know the answer. We're taking the stress off that beta cell. We're taking the stress off that beta cell to have to produce a lot of insulin. We're making that beta cell do what? 

45:03
Dr. William Seeds
Survive, adapt, do all these beautiful things we wanted to do to last longer, to deal with. With glucose longer. This is where it all begins. God, this is also awesome because we can. That's a great question. And I didn't even. This is why this is so much fun. Let me finish. So, so postprandial hyperglycemia is dangerous. Why? Because let's say you start developing insulin resistance, where you're not pulling that glucose in and that glucose stays out there. Well, the question is, well, if I have high glucose after I eat and it doesn't go down, what is that? Doing things. Is that bad? Yes, because that glucose, what it does is, has a way of then changing proteins and messaging of other peptides, proteins. It changes cell signaling. It adds to stress. They're called n glycation products. And all these things that happen. 

46:20
Dr. William Seeds
And we'll get into that. But. But it's a bad thing because your beta cell that senses all that glucose out there is working overtime to make even more insulin, creating more oxidative stress. It can't produce enough antioxidants to control that stress, which is what? Yes, redox. Right. The redox of that cell is just going bonkers. And so the survival now and the resilience of that cell is being compromised. And that's what leads to loss of beta cells, apoptosis, which just means the dying of the cell. And what happens then? Well, then you lose the ability to produce insulin. Right. It's what happens gradually over time. That is the essence of the beginning of so many disease processes. Autoimmune problems, cancer, you name it. We can start right there. Awesome question. So if you walk, let's just say your insulin resistance too. 

47:32
Dr. William Seeds
Well, what did we just hear? If you get up and walk, that muscle says, I don't need any signaling. Give me that glucose. 

47:39
Matthew Seeds
So to wrap up the conversation on beta cells, what you're saying is as long as you're eating, there's an activity threshold that's going to be hit and it's either going to be fully absorbed by the beta cell or if you get moving, you can take some of that pressure off of the beta cell. So it's who's going to put in the work? You or your beta cells. 

47:58
Dr. William Seeds
Excellent. I mean, it's re. You you just talked about globally or from a macro level, you talked about redox where every cell, everything we do is all about making redox better. And you've just said, okay, if we exercise, we're making redox easier for that beta cell to continue its function. And all that takes. 

48:28
Madison Lepore
Is a 20 minute walk. 

48:30
Dr. William Seeds
20 minute walk. After you eat, after every meal. Do you know we could probably change type 2 diabetes around the world? This is no shit. We could put tremendous diet dent in type 2 diabetes. That is, that is actually. Oh my gosh. We could get into all of that too. It's what, by 2045 there's going to be over 700 million people that are in that state. It's going to be an $845 billion expense. 

49:08
Matthew Seeds
Hey, hey, hey. Financial numbers are mine. You stick to the science. 

49:11
Madison Lepore
Please don't take that from Matt. 

49:14
Matthew Seeds
Yeah, I got one thing. 

49:15
Dr. William Seeds
Okay. I'm sorry about that. 

49:17
Madison Lepore
You're also the host. You got like two things. 

49:20
Dr. William Seeds
Anyways, gosh, guys, this was awesome. I. I hope you understand. You just gave me the, you gave me that lead in of where if I can make science cool if I can give people the empowerment of understanding just some simple things about Hey, I eat. Hey, glucose goes up. Hey, glucose up is a bad thing because that. And it's the most dangerous. People hear that. What? When I eat, that's the most dangerous time in my life. Absolutely is. Because it puts this stress on this cell that is just so. 

49:57
Dr. William Seeds
It's so amazing if you understand this and then you know at some point will link in this GLP1 stuff for so people to really understand the incredible medical breakthrough of this peptide and how it relates to just what I said and not listen to all of this craziness about something that's out there about GLP1s and so forth. 

50:22
Matthew Seeds
Maybe you should change that sentence then. Instead of eating being the most dangerous time your life. Eating being the most dangerous time of your cell's life. 

50:30
Madison Lepore
Yeah, let's not make people afraid to eat and cause like a national eating disorder. Just. 

50:36
Dr. William Seeds
Yeah, no, you're right. I get a little too excited. It's just understanding what sets up the process of problems with. 

50:48
Madison Lepore
With Redox. 

50:49
Dr. William Seeds
With Redox. It's a. It's a great example of why when we're young and then why when we're older do we have these problems with food and life and so forth? Well, it's all because there's only a spec that you've only got so many beta cells that can handle so much stress over time. And there's some cool things. We'll talk about how beta cells can be. Beta cell mass can be regenerated, all this really awesome stuff. But it's why in a younger person they've got plenty of beta cell mass and an older person doesn't have that. And so that's why you see these difficulties with insulin and glucose and muscle building and disease. And it's why aging is a precursor for everything we know in disease processes. Cataracts and sarcopenia, that's muscle loss, osteopenia, bone loss, and that's cardiovascular disease, neurodegenerative disease. 

51:51
Matthew Seeds
All that's something you point out a lot. Why it's so important that the WHO has officially recognized aging as a disease. 

52:00
Dr. William Seeds
Finally. I hope you've enjoyed our first episode. This has been so much fun, guys. We are going to change the world with education here. And I am so stoked, fired up. I can't tell you how cool this is to be able to talk finally and have you guys helped me relate the message. This is just exciting. And I want Everybody out there, I want you to participate with us. I want you to ask us questions. I want you to throw stuff at us. Let me hear it, because then maybe I can respond to it. I, I, I'm gonna learn. Please say, hey. 

52:36
Madison Lepore
Doctor sees. Looks like you need to go to the gym. 

52:38
Dr. William Seeds
Oh, they're gonna hurt me. Don't say that. I'm in a cutting phase right now. People don't realize this since I'm gonna just say this right now. December till now was this timeframe because I was going on this journey of I'm setting up myself. I hit some plateaus with my strength. The way to work through it is I took the approach of working on improving my. The stemness and quiescence of my stem cells, ready to help rebuild muscle, which we'll get into. I know how to do this. I'm 63. You got to know how to do things to get through plateaus as you get older and get stronger and look appropriate. So great. Thanks for being with us. This has been so exciting. I want to keep talking forever and ever, but thank you, Matty. 

53:31
Madison Lepore
Thank you. 

53:32
Dr. William Seeds
Thank you, Matthew. 

53:34
Matthew Seeds
And we touched on it today. But in the next episode, we're going to cover much more on GOP1s, and we will be joined by special guest Jock Putney, CEO of Nuvolum, who has over 30 years in the healthcare space, and he's also a frequent gym goer and some might say looking a little bigger than you right now. 

53:55
Dr. William Seeds
And he's. We have to come full circle here, too. He's an umbrella patient. You don't even know what an umbrella patient is, do you? 

54:03
Matthew Seeds
I don't know what a pancreas is. 

54:06
Dr. William Seeds
Well, we'll get into that in the next episode. 

54:08
Matthew Seeds
Hey, if you want more information, please make sure to subscribe to both RWilliam Seeds and Redox Medical Group on YouTube and Instagram.